BPH is an enlargement of the prostate. The epithelial and stromal cells of the prostate increase in size, resulting in the formation of large nodules in the peri-urethral region close to the prostate.
They become fairly large and the nodules compress the urethral canal, making urination difficult.
Other symptoms are
-Frequent urination
-Urination at night
-Weak urinary stream
-Prolonged urination
-Incontinence
-Urination dribble
-Painful ejaculation
The cause is unknown, but is linked to the hormone, testosterone. Hence, men who have been castrated do not develop BPH.
It is a common condition and risks men of urine retention, urinary tract infection and bladder stones (due to crystallisation of salts in residual urine)
BPH starts to develop in a man's 30's and progresses till symptoms appear in the 50's. It does not lead to prostate cancer.
TREATMENT
-Watchful waiting
-Drug of choice is alpha1 adrenergic receptor antagonists such as doxazosin,
terazosin, silodosin etc
-Surgery
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